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Figure 5 | BMC Evolutionary Biology

Figure 5

From: Evolutionary cores of domain co-occurrence networks

Figure 5

Overlap of domain co-occurrence networks. (a) We define the overlap of two networks as the edges, and their concomitant nodes, common to both networks. (b) The overlap of the four innermost k-cores of the co-occurrence domain graphs of S. cerevisiae, C. elegans, D. melanogaster, M. musculus and H. sapiens only shows a small number of conserved edges (red: 1-core, yellow: 2-core, green: 3-core, blue: 4-core). The overlap of the 1-cores consists of a fully connected kernel populated by signaling domains. Nesting outward in the overlap of the 2, 3, 4-cores ((b),(c)), domains that are responsible for signal transduction such as zinc-fingers and cell-cell contacts are dominating.

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