Table 1 The twelve families of universally conserved genes missing in mammals
Gene Family Name1 | A.t2 | S.c2 | A.g2 | D.m2 | C.e2 | Loss extends to | Function | EC | KEGG pathway |
|---|---|---|---|---|---|---|---|---|---|
ACH | 0 | 1 | 1 | 1 | 1 | Deutero. | Acetyl-CoA Hydrolase, Pyruvate Metabolism | 3.1.2.1 | sce00620 |
TPS | 4 | 1 | 1 | 1 | 2 | Deutero. | Trehalose 6P biosynthesis | 2.4.1.15 | Sce00500 |
YD56 | 4 | 3 | 2 | 1 | 1 | Chordates | Multicopper Ion transporter | 1.-.-.- | XXX |
YMT1 | 1 | 1 | 1 | 3 | 1 | Chordates | Putative oxidroeductase and K+ ion transporter | XXX | XXX |
PNC1 | 0 | 1 | 1 | 1 | 1 | Chordates | Nicotinate and Nicotinamide Metabolism | 3.5.1.19 | sce00760 |
YM74 | 3 | 2 | 1 | 1 | 1 | Chordates | Transcription factor activity/DNA Binding | XXX | XXX |
THDH1/ILV1 | 1 | 1 | 1 | 1 | 2 | Chordates | Leucine, Isoleucine, Valine Biosynthesis. Threonine Metabolism | 4.3.1.19 | sce00260 |
GLT | 1 | 1 | 1 | 1 | 1 | Chordates | Glutamate synthesis | 1.4.1.13 | sce00251 sce00910 |
AMT/MEP -1,2,3 | 6 | 3 | 1 | 1 | 4 | Eu-chordates | Amonium Transporter | XXX | XXX |
YKH1 | 0 | 1 | 1 | 1 | 9 | Mammals | Metabolism, oxidoreductase | XXX | XXX |
URH1 | 2 | 1 | 3 | 3 | 2 | Mammals | Uridine catabolism, hydrolase activity | 3.2.2.3 | XXX |