Phase distribution of spliceosomal introns: implications for intron origin

Table 2 Prediction of intron phase distributions using the all-pattern intron insertion model and mutation correction.

Organism	Best mrate	Best %GC	Phase distribution (%)			Error	σ
			P-0	P-1	P-2
N. crassa	-0.004	55.9	38.2	34.2	27.6	0.08*	0.001
D. melanogaster	-0.011	53.5	42.8	32.6	24.6	19.58	0.055
H. sapiens	+0.178	55.0	45.4	31.1	23.5	0.27*	0.066
F. graminearum	+0.163	54.3	38.7	34.7	26.6	1.75*	0.024
C. neoformans	+0.503	59.9	41.7	31.1	27.2	4.09*	0.125
X. tropicalis	+0.279	52.3	46.7	30.1	23.2	1.41*	0.138
A. thaliana	+0.632	57.6	57.5	20.7	21.8	0.69*	0.147
C. elegans	+0.539	54.6	48.6	28.4	23.0	274.98	2.260
S. pombe	+0.406	49.2	42.3	33.3	24.4	13.39	0.099
P. falciparum	+0.390	34.7	42.3	30.9	26.8	56.88	0.347

"Best mrate" shows the best mutation rate. "Best %GC", "phase distribution (%)", and "error" are averages of 20 simulations for mutation correction at the best mutation rate. Error is measured as the χ² value between the observed and predicted intron phase distributions. "σ" shows the standard deviation of error in 20 simulations. P-0, phase-0; P-1, phase-1; P-2, phase-2.
* Not significant at the P < 0.05 level. All other comparisons were significant.

ISSN: 2730-7182