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Table 1 Relative evolutionary rates of Tribolium castaneum, and the dipterans Anopheles gambiae and Drosophila melanogaster. Amino acid distances, divergence time estimates, and substitution rates for the holometabolous insect branches and the base of Diptera are shown.

From: Genome-wide acceleration of protein evolution in flies (Diptera)

Branch (from node..to node)

Distance [aa subs/site]

Timea [My]

Rate [10-3 aa subs/site/My]

Relative rateb

Tribolium (1..4)

0.180 ± 0.003

280.0 ± 4.4

0.643 ± 0.015

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Anopheles – base (3..4)

0.222 ± 0.003

280.0 ± 4.4

0.793 ± 0.016

1.233 ± 0.038

Drosophila – base (2..4)

0.245 ± 0.003

280.0 ± 4.4

0.875 ± 0.017

1.361 ± 0.041

Anopheles (3..5)

0.145 ± 0.002

241.0 ± 4.0

0.602 ± 0.013

0.936 ± 0.030

Drosophila (2..5)

0.168 ± 0.002

241.0 ± 4.0

0.697 ± 0.014

1.084 ± 0.033

Base of Diptera (4..5)

0.077 ± 0.002

39.0 ± 5.9

1.974 ± 0.303

3.071 ± 0.477

  1. a Age of geological stage as defined in "A Geologic Time Scale" [39] (see text for details).
  2. b Relative rate = Rate/(Tribolium Rate)