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Table 3 Average GO similarity for mammalian gene coexpression networks versus average GO similarity for all gene pairs

From: Global similarity and local divergence in human and mouse gene co-expression networks

Species

netGOavg 1

allGOavg 2

t 3

P 4

Human

0.2637 ± 9.1e-4

0.1989 ± 4.9e-5

80.78

0

Mouse

0.2736 ± 8.9e-4

0.2150 ± 8.2e-5

75.23

0

  1. 1Average GO similarities for all pairs of genes connected by an edge in the coexpression network
  2. 2Average GO similarities all possible pairs among the 9,105 human-mouse orthologs
  3. 3Value of test statistic, t = (μ1-μ2)/(σd*sqrt(1/n1+1/n2)) where μ are the respective means and σd is the standard deviation of the difference
  4. 4Level of significance based on Students t-distribution with degrees of freedom = n 1+n 2-2