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Table 2 Analysis of markers common to 5 species

From: Recurring genomic breaks in independent lineages support genomic fragility

Fixed species # blocks Variable species 1 (# breaks) Variable species 2 (# breaks) #joint breaks (β Avg #joint breaks in shuffles p-value of correlated break (βp)
hg,mus 126798 canis(127) rn(421) 3 2.4 0.441
hg,rn 122981 canis(111) mus(69) 0 0.3 1
canis,mus 121649 hg(81) rn(416) 0 1.8 1
canis,rn 117204 hg(84) mus(69) 1 0.3 0.286
hg,mus 126798 gal(1224) rn(421) 33 19.1 0.002
hg,rn 122981 gal(1152) mus(69) 6 2.6 0.036
gal,mus 47121 hg(17) rn(60) 0 0.1 1
gal,rn 46049 hg(19) mus(19) 1 0 0.01
canis,mus 121649 gal(1253) rn(416) 35 19.8 0.001
canis,rn 117204 gal(1187) mus(69) 8 3 0.011
gal,mus 47121 canis(20) rn(60) 1 0.1 0.126
gal,rn 46049 canis(19) mus(19) 1 0 0.047
canis,hg 123305 gal(1278) rn(582) 67 30.5 0
canis,rn 117204 gal(1187) hg(84) 9 4.4 0.05
gal,hg 38367 canis(17) rn(55) 0 0 1
gal,rn 46049 canis(19) hg(19) 3 0 0
canis,hg 123305 gal(1278) mus(229) 37 12.3 0
canis,mus 121649 gal(1253) hg(81) 8 4.4 0.081
gal,hg 38367 canis(17) mus(30) 0 0.1 1
gal,mus 47121 canis(20) hg(17) 1 0 0.021
  1. For Minimum flank = 2 and Rank differential = 3, the table shows the number of breaks in the variable species, the number of joint breaks, the average number of joint breaks in 1000 random shuffles and the p-value of the joint breaks. This is based on greater than 100 bps markers common to Human, Mouse, Rat, Dog and Chicken. This is based on FBP. In all 20 combinations both variable species have at least 10 breaks and 55% exhibit significant joint breaks.