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Table 3 Analysis of markers common to 4 species

From: Recurring genomic breaks in independent lineages support genomic fragility

Minimum Flank Fixed species # blocks Variable species 1 (# breaks) Variable species 2 (# breaks) #joint breaks (β Avg #joint breaks in shuffles p-value of correlated break (βp)
2 hg,mus 403240 canis(741) rn(1067) 17 10.4 0.025
2 hg,rn 394250 canis(709) mus(451) 9 3.7 0.009
2 canis,mus 380087 hg(352) rn(982) 5 5.7 0.677
2 canis,rn 369584 hg(332) mus(383) 2 1.6 0.453
3 hg,mus 406346 canis(599) rn(858) 16 7.5 0.006
3 hg,rn 394036 canis(566) mus(311) 9 2.4 0
3 canis,mus 378865 hg(303) rn(797) 5 4.4 0.423
3 canis,rn 364549 hg(283) mus(257) 2 1.1 0.31
  1. For Rank differential = 2, the table shows the number of breaks in the variable species, the number of joint breaks, the average number of joint breaks in 1000 random shuffles and the p-value of the joint breaks, for FBP. This is based on greater than 500 bps markers common to Human, Mouse, Rat, and Dog. 4 of the 8 combinations have significant joint breaks.