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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

Figure 2

PE/PPE gene structure. (A) Diagrammatic representation of the gene structure of the members of the PE and PPE gene family, showing conserved N-terminal domains, motif positions and differences between different subfamilies found in the two families [12,16]. (B) Alignment of the region surrounding the SVP motif Gly-X-X-Ser-Val-Pro-X-X-Trp in the members of the PPE-SVP subfamily. (C) Alignment of the region surrounding the GFGT motif (Gly-Phe-X-Gly-Thr) and PPW motif (Pro-X-X-Pro-X-X-Trp) in the members of the PPE-PPW subfamily.

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