Figure 5

Breakpoints density plot along the alignment of mcyB and mcyC genes. Light grey and dark grey areas respectively indicate local 99% and 95% breakpoint clustering thresholds taking into account regional differences in sequence diversity that influence the ability of different methods to detect recombination breakpoints. The broken line in the breakpoint density graph indicate 95% confidence thresholds for globally significant breakpoint clusters. The boundary between the condensation, adenylation and thiolation domains is indicated with a solid line.