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Figure 5 | BMC Evolutionary Biology

Figure 5

From: DNA indels in coding regions reveal selective constraints on protein evolution in the human lineage

Figure 5

Distribution of dN / dS values among indel containing genes. The histograms show the measured distributions of gene frequencies with dN/dS values in binned intervals of length 0.1, starting from 0. Gene frequencies are generally peaked in the interval 0 ≤ dN/dS ≤ 0.1 and decay for larger dN/dS values, indicating strong purifying selection on protein coding regions throughout evolution. However, the distributions of the subsets of genes that contain at least one insertion/deletion decay slower compared to the background distribution of all analyzed genes.

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