
Called not significant

Called significant

Total


Null true

U

V

m
_{0}

Alternative true

T

S

m  m
_{0}

Total

M  R

R

m

 N_{
s
}, total number of experimentally verified miRNA sequences; Length, distribution of miRNA sequence length; %GC, distribution of GC content of miRNA sequences; No. of genetically (environmentally) robust miRNAs (%), the number of significantly genetically (environmentally) robust miRNAs (%) at FDRcontrolled Pvalue of < 0.05, comparing with random pseudo premiRNAs.