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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Evolutionary genomic remodelling of the human 4q subtelomere (4q35.2)

Figure 2

Localisation of D4Z4 and LINE sequences on gorilla (GGO) (A) and chimpanzee (PTR) (B) 4q stretched chromosomes. The reciprocal localisation was derived by dual colour FISH using a gorilla D4Z4 unit (yellow signals) and a LINE probe (red signals). Figures A and B show the hybridisation patterns obtained using a single probe (D4Z4 and LINE inserts), and the merged hybridisation (merged). C) Schematic representation of gorilla (GGO), chimpanzee (PTR) and human (HSA) 4qter genomic organisations. The gorilla and chimpanzee organisations were derived from the molecular and FISH data herein, whereas the human organisation is taken from previous studies (for a review, see van der Maarel et al., 2006). The question mark (?) indicates that the length of the D4Z4 array in chimpanzee was not determined. Double asterisks (**) indicate the overlapping region between the LINE block and subtelomeric block 3 in the human genome [20].

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