Figure 2

Ectopic gene conversion affecting array Tb105a (expression-site associated gene, Tb10.6k15.0910), identified by distribution criterion. A. GENECONV output, showing significant similarity between regions in an alignment of gene copies 2 and 3 and another gene at a locus in trans (Tb10.70.2860). Regions of significant similarity are represented by coloured rectangles, where colour refers to the two sequences concerned (blue: Tb105a.2 and Tb105a.3; red: Tb105a.2 and Tb10.70.2860; green: Tb105a.3 and Tb10.70.2860). Dashed lines denote significance thresholds. B. Diagram of the chromosomal position of Tb105a. Dashed green lines link Tb105a.3 with significant breakpoints in the alignment. C. Phylogenetic network of Tb105a gene copies and related loci throughout the genome, produced using the Neighbour-Net algorithm in Splitstree v4.0. The dashed green line shows the direction of the putative ectopic gene conversion.