Figure 5

The effect of ESEs on fourfold degenerate site divergence and the ncRNA gene distributions observed across chromatin categories. (A+B) The observed rate of transitions and transversions respectively, at fourfold degenerate sites with and without ESE sites excluded (Fourfold degenerate site transversions r²: = 0.02, p = 0.69; fourfold degenerate site transversions at non-ESE sites r²: = 0.13, p = 0.30; intergenic transversions r²: = 0.92, p = 1.2e-05. Fourfold degenerate site transitions r²: = 0.78, p = 0.001; fourfold degenerate site transitions at non-ESE sites r²: = 0.67, p = 0.004; intergenic transitions r²: = 0.81, p = 4.0e-04). (C+D) The percentage of genes in each chromatin category that are of each Ensembl ncRNA class. Only the distributions of rRNAs and snRNAs show a significant negative correlation with chromatin structure (rRNA r²: = 0.96, p = 0.004; snRNA r²: = 0.92, p = 0.01)