Table 1 Additional parameters introduced in the R5 to X4 phenotypic switch model.
Parameter | Symbol | Value | Units of Meas. |
|---|---|---|---|
Production of immature T cells | N U | 100 | cell/Ī¼ l t-1 |
Death rate of immature T cells | Ī“ U | 0.1 | t -1 |
Death rate of immature T cells upon the interaction with TNF |
| 10-5 | Ī¼ l/cell t-1 |
Decreasing infectivity of R5 phenotype due to TNF | k R 5 | 10-7 | (Ī¼l/ cell)2 t-1 |
Increasing infectivity of R5 phenotype due to TNF | k X 4 | 10-7 | (Ī¼l/ cell)2 t-1 |
Increasing death rate of immature T cells due to TNF |
| 0.0005 | Ī¼ l/cell t-1 |
Rate of production of TNF | k F | 0.0001 | t -1 |