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Table 5 Sequence Identities of the Ciona VDR/PXR to Other Nuclear Hormone Receptors

From: Evolution of pharmacologic specificity in the pregnane X receptor

Receptor % Identity to Ciona VDR/PXR in DBD % Identity to Ciona VDR/PXR in LBD
Human PXR 61.8 22.5
Mouse PXR 60.3 21.5
Chicken PXR 63.2 23.7
Xenopus laevis PXRα 64.7 20.3
Fugu PXR 67.6 19.8
Human VDR 67.6 17.1
Zebrafish VDR 70.6 21.8
Sea lamprey VDR 73.5 20.8
Human CAR 60.3 26.8
Mouse CAR 55.9 23.2
Human FXR 54.4 23.1
Zebrafish FXR 55.9 24.0
Ciona FXR 55.2 21.9
Human LXRa 54.4 21.9
Zebrafish LXR 54.4 19.8
Ciona LXR 52.9 19.3