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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Experimental manipulation of immune-mediated disease and its fitness costs for rodent malaria parasites

Figure 2

Total parasite densities were lower during IL-10R blockade, regardless of P. c. chabaudi parasite genotype. Line graphs represent the dynamics of total parasite density in αIL-10R (filled symbols) or control IgG (open symbols) treated mice during single-clone infections with each of eight P. c. chabaudi clones. Each line represents the mean of five mice (± S.E.), except where deaths had occurred. Regardless of P. c. chabaudi parasite genotype, neutralizing IL-10R resulted in lower total parasite densities between days 3 to 21 p.i. and lower early parasite densities (days 3–8 p.i.) compared to control mice.

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