Evidence against the energetic cost hypothesis for the short introns in highly expressed genes

Table 2 Comparison of compactness between genes expressed at different levels^a

	Average intron length	Total intron length	Intron number	CDS length	UTR length	Expression level
Human genes
Top 30% quantile	2768 ± 608	28117 ± 7347	8 ± 1	1313 ± 90	775 ± 107	5369 ± 770
Versus
Bottom 30% quantile	10448 ± 4237	901046 ± 33210	9 ± 1	1764 ± 232	1478 ± 244	267 ± 14
	P = 0.001	P = 0.019	P = 0.844	P = 0.273	0.019
Mouse genes
Top 30% quantile	2631 ± 290	16190 ± 1828	7 ± 1	1214 ± 65	779 ± 136	6219 ± 794
versus
bottom 30% quantile	8032 ± 2706	37391 ± 4615	8 ± 1	1450 ± 128	1496 ± 190	365 ± 16
	P = 0.001	P = 0.001	P = 0.444	P = 0.589	P = 0.001

^a The human genes and the mouse genes are those analyzed in Figure 1. We used the Mann-Whitney U test to determine the significance of differences. For each case, we present the average value ± standard error of mean.

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