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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Molecular evolution of Cide family proteins: Novel domain formation in early vertebrates and the subsequent divergence

Figure 1

The analysis of Cide and Dff family proteins in human and mouse. (A) Sequence alignment of the N-terminals of all available Cide and Dff family proteins in human and mouse using MAFFT algorithm. The CIDE-N domain is indicated by a dark line on top of the alignment. The alignment of the most conserved region of 37 amino acids encompassing the EDGT signature motif is framed with a red rectangle. The signatures of Cide and Dff family proteins are framed with a green rectangle. The exon boundaries are marked by black vertical lines. (B) Sequence alignment of the CIDE-C domains of Cide family proteins found in human and mouse using MAFFT algorithm. The CIDE-C domain is indicated by a dark line on top of the alignment. The alignment of most conserved 35 amino acids is framed with a red rectangle. The exon boundaries are marked by black vertical lines.

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