Table 1 Ecological and genomic context of the fur homologues

Acidothermus cellulolyticus 11B

NC_008578

2,4

67

Acel_2095

A

67,1

aquatic; aerobic; thermophilic

Acel_0061

E

64,9

Acel_2085

B

65,5

Arthrobacter aurescens TC1

NC_008711

4,6

62

AAur_3058

A

60,6

terrestrial – can transform heavy metals into less toxic forms; aerobic; mesophilic

AAur_2630

B

61,1

Arthrobacter sp. FB24

NC_008541

4,7

66

Arth_3077

A

65,8

terrestrial – high degree of tolerance to chromium and other metals, may be radiation resistant and is a hydrocarbon degrader; mesophilic

Arth_2638

B

68,2

Bifidobacterium adolescentis ATCC 15703

NC_008618

2,1

59

BAD_0517

B

62,2

host-associated – normal inhabitant of the healthy human gut; anaerobic; mesophilic

Bifidobacterium longum NCC2705

NC_004307

2,3

60

BL1128

B

61,2

host-associated – normal component of gut flora; anaerobic; mesophilic

Corynebacterium diphtheriae NCTC 13129

NC_002935

2,5

54

DIP1710

B

51,5

multiple – human pathogen, causative agent of diphtheria; aerobic; mesophilic

Corynebacterium efficiens YS-314

NC_004369

3,1

63

CE2180

B

63,1

multiple; facultative aerobic; mesophilic

Corynebacterium glutamicum ATCC 13032

NC_006958

3,3

54

NCgl2200

B

53,3

multiple; facultative aerobic; mesophilic

Corynebacterium jeikeium K411

NC_007164

2,5

61

jk0612

B

62,5

multiple – member of the human skin flora, opportunistic pathogen; facultative aerobic; mesophilic

Frankia alni ACN14a

NC_008278

7,5

73

FRAAL3168

A

72,0

free-living or in symbiosis with plants roots; aerobic; mesophilic

FRAAL0074

B

72,0

FRAAL5117

C

71,4

FRAAL2798

E

76,4

Frankia sp. CcI3

NC_007777

5,4

70

Francci3_3112

C

70,3

free-living or in symbiosis with plants roots; aerobic; mesophilic

Francci3_2661

E

73,9

Francci3_0061

B

71,8

Frankia sp. EAN1pec

NZ_AAII00000000

9,0

71

Franean1_1532

A

70,3

free-living or in symbiosis with plants roots; aerobic; mesophilic

Franean1_1806

C

73,2

Franean1_6149

E

72,4

Franean1_7263

B

74,1

Leifsonia xyli subsp. xyli str. CTCB07

NC_006087

2,6

68

Lxx02790

A

70

host-associated; plant pathogen; aerobic; mesophilic

Lxx25010

B

69,1

Mycobacterium avium 104

NC_008595

5,5

69

MAV_2752

A

68,9

host-associated – mammal pathogen; aerobic; mesophilic

MAV_2036

B

68,4

Mycobacterium avium subsp. paratuberculosis K-10

NC_002944

4,8

69

MAP1669c

A

68,7

multiple – mammal pathogen, causative agent of Johne's disease or paratuberculosis; aerobic; mesophilic

MAP2139

B

67,9

Mycobacterium bovis AF2122/97

NC_002945

4,3

66

Mb1944c

A

62,3

host-associated – mammal pathogen, causative agent of classic bovine tuberculosis; aerobic; mesophilic

Mb2380

B

62,8

Mycobacterium bovis BCG str. Pasteur

NC_008769

4,4

66

BCG_1948c

A

62,0

host-associated – mammal pathogen, causative agent of classic bovine tuberculosis; aerobic; mesophilic

BCG_2373

B

62,8

Mycobacterium leprae TN

NC_002677

3,3

58

ML0824

B

59,1

host-associated – human pathogen, causative agent of leprosy; aerobic; mesophilic

Mycobacterium smegmatis str. MC2 155

NC_008596

7,0

67

MSMEG_6253

A

67,3

host-associated – human pathogen; aerobic; mesophilic

MSMEG_6383

A

70,6

MSMEG_3460

A

64,9

MSMEG_4487

B

70,6

Mycobacterium sp. JLS

NC_009077

6,0

68

Mjls_2712

A

68,5

multiple; mesophilic

Mjls_5253

A

72,7

Mjls_3458

B

71,1

Mycobacterium sp. KMS

NC_008705

5,7

68

Mkms_2726

A

68,8

multiple; mesophilic

Mkms_4974

A

72,2

Mkms_3510

B

71,5

Mycobacterium sp. MCS

NC_008146

5,7

69

Mmcs_2681

A

66,5

multiple; mesophilic

Mmcs_4885

A

72,2

Mmcs_3447

B

71,5

Mycobacterium tuberculosis CDC1551

NC_002755

4,4

66

MT1960

A

62,3

host-associated – human pathogen, causative agent of tuberculosis; aerobic; mesophilic

MT2428

B

62,6

Mycobacterium tuberculosis H37Rv

NC_000962

4.4

66

Rv1909c

A

62,3

host-associated – human pathogen, causative agent of tuberculosis; aerobic; mesophilic

Rv2359

B

62,6

Mycobacterium ulcerans Agy99

NC_008611

5,6

66

MUL_2189

A

63,8

host-associated – human pathogen, causative agent of Buruli or Bairnsdale ulcer; aerobic; mesophilic

MUL_3612

B

65,2

Mycobacterium vanbaalenii PYR-1

NC_008726

6,5

68

Mvan_2983

A

69,3

multiple; aerobic; mesophilic

Mvan_3209

A

65,8

Mvan_3820

B

67,9

Nocardia farcinica IFM 10152

NC_006361

6,0

71

nfa3250

A

75,0

multiple – opportunistic pathogens in a broad range of species; aerobic; mesophilic

nfa29490

A

68,5

nfa14570

B

70,2

Nocardioides sp. JS614

NC_008699

5,0

72

Noca_0839

A

74,5

terrestrial; aerobic; mesophilic

Noca_0874

A

75,1

Noca_4251

E

70,2

Noca_1934

B

74,0

Propionibacterium acnes KPA171202

NC_006085

2,6

60

PPA0948

B

57,0

host-associated – opportunistic human pathongen, causative agent of acne; anaerobic; mesophilic

Rhodococcus sp. RHA1

NC_008268

7,8

68

RHA1_ro04308

A

67,5

terrestrial; aerobic; mesophilic

RHA1_ro05274

A

66,2

RHA1_ro01222

B

67,4

Rubrobacter xylanophilus DSM 9941

NC_008148

3,2

71

Rxyl_1228

-

67,6

specialized – exhibits high tolerance to radiation; aerobic; thermophilic

Rxyl_1140

-

68,0

Rxyl_1144

-

75,6

Streptomyces avermitilis MA-4680

NC_003155

9,0

71

SAV3053

D

71,9

multiple – mainly found in the soil; aerobic; mesophilic

SAV4029

E

64,8

SAV5631

B

70,7

Streptomyces coelicolor A3(2)

NC_003888

8,7

72

SCO0561

A

74,3

multiple – mainly found in the soil; aerobic; mesophilic

SCO5206

D

72,2

SCO4180

E

66,4

SCO2508

B

72,6

Thermobifida fusca YX

NC_007333

3,6

68

Tfu_0145

Tfu_0856

A

B

68,8

64,6

multiple – mainly found on self-heated organic materials, its spores are known to cause allergic respiratory diseases; aerobic; thermophilic

Tropheryma whipplei TW08/27

NC_004551

0,9

46

-

-

Host-associated – human pathogen, causative agent of Whipple's disease; aerobic; mesophilic

Tropheryma whipplei str. Twist

NC_004572

0,9

46

-

-

Host-associated – human pathogen, causative agent of Whipple's disease; aerobic; mesophilic