Phylogenetic tree of the 17 human Hsp70 proteins and the proteins that would be encoded in the related pseudogenes identified in this work. Same as tree shown in Figure 1 but including the most conserved pseudogenes (see text). Shaded areas highlight each group of pseudogenes with the gene from which they originated, indicated by an asterisk. A similar tree (not shown) was obtained using the maximum-likelihood approach implemented in the program PHYML . See legend for Figure 1 and text for details on Methods.