Skip to main content
Figure 5 | BMC Evolutionary Biology

Figure 5

From: Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties

Figure 5

Phylogenetic analysis of human (h) and mouse (m) TRIM and TRIM-like proteins from Group 2. TRIM proteins are indicated with their TRIM number ('incomplete' TRIM proteins are indicated with their alternative TRIM number with an asterisk, see Table 1). No invertebrate TRIM proteins are represented in this group. Bootstrap support values above 50% based on 1000 replicates are shown. Group 1 TRIM37 sequences are used as outgroup. The scale of amino acid sequence divergence is indicated at the bottom right corner. Twenty-four pairs of orthologs can be identified (gray-shadowed branches). The remaining proteins can be subdivided in three different types, based on the phylogenetic relationship with their neighbors: (i) Proteins that are present only in one species and apparently started to diverge from their paralogs before human-mouse split (green clades); (ii) Clades of paralogous proteins that are present only in human and share a single homologous counterpart in mouse (red-shadowed branches); (iii) Clades of paralogous proteins that are present only in mouse and do not have any obvious homologous counterpart in humans (blue-shadowed branches).

Back to article page