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Table 7 Likelihood ratio tests of positive selection

From: Evidence for positive selection acting on microcystin synthetase adenylation domains in three cyanobacterial genera

Genus

Region analyzed

Model

lnL

Estimates of parameters

ω§

Positively selected sites#

LRT

Anabaena

mcyB1

M7 (beta)

-2249.981

p = 0.005, q = 0.01858

 

Not allowed

40.966***

  

M8 (beta and ω)

-2229.498

p0 = 0.997, p = 0.005, q = 0.021

p1 = 0.003, ω = 94.065

0.492

243W, ω = 3.717*

278C, ω = 3.935**

414L, ω = 4.053***

 

Anabaena

mcyC

M7 (beta)

-1695.094

p = 0.005, q = 0.0471

 

Not allowed

20.476***

  

M8 (beta and ω)

-1684.856

p0 = 0.945, p = 0.005, q = 2.205

p1 = 0.055, ω = 6.562

0.362

125N, ω = 6.994*

148D, ω = 8.098***

151Q, ω = 7.518**

202I, ω = 6.992*

203T, ω = 7.240**

205Q, ω = 7.240***

223G, ω = 7.177**

278S, ω = 7.176**

 

Microcystis

mcyB1

M7 (beta)

-2321.128

p = 0.005, q = 0.016

 

Not allowed

6.729**

  

M8 (beta and ω)

-2318.527

p0 = 0.942, p = 0.110, q = 0.773

p1 = 0.058, ω = 2.584

0.356

350T, ω = 2.879***

352I, ω = 2.792***

389Q, ω = 2.727*

404Q, ω = 2.744*

420E, ω = 2.684*

 

Microcystis

mcyC

M7 (beta)

-2674.333

p = 0.012, q = 0.0416

 

Not allowed

16.516***

  

M8 (beta and ω)

-2666.075

p0 = 0.976, p = 0.015, q = 0.0811

p1 = 0.024, ω = 4.939

0.280

158Q, ω = 3.471***

205R, ω = 3.472***

300A, ω = 3.279*

349R, ω = 3.481***

438L, ω = 3.473***

 

Planktothrix

mcyB1

M7 (beta)

-2030.973

p = 0.005, q = 0.021

 

Not allowed

7.93***

  

M8 (beta and ω)

-2027.008

p0 = 0.896, p = 0.005, q = 1.883

p1 = 0.104, ω = 2.134

0.231

259N, ω = 3.074***

262P, ω = 3.187***

278F, ω = 3.005***

347A, ω = 3.000*

 

Planktothrix

mcyC

M7 (beta)

-1595.526

p = 50.84, q = 99.000

 

Not allowed

0.002

  

M8 (beta and ω)

-1595.525

p0 = 1.000, p = 50.442, q = 99.00

p1 = 0.000, ω = 0.539

0.196

None

 
  1. § calculated using estimates of parameters of best fitting model
  2. # numbering of amino acid residues according to GrsA (swissprot: P0C061)
  3. *90% confidence interval level
  4. ** 95% confidence interval level
  5. *** 99% confidence interval level