Figure 1
From: Evolutionary analysis of the highly dynamic CHEK2duplicon in anthropoids
FISH with a CHEK2 duplicon containing Y-chromosomal cosmid probe in anthropoids. (A): Schematic representation of the human Y chromosome with an enlarged view of the CHEK2 duplicon in Yq11.1/Yq11.21. Basepair positions within the Y-chromosomal contig NT_113819 are indicated for the CHEK2 duplicon boundaries, for all probes used to identify a CHEK2 duplicon containing cosmid and for the derivative CAGGG repeat sequences. Localization of FISH probe LLOYNC03'M'22E01 within the Y-chromosomal contig is shown below. (B) Comparative FISH of cosmid LLOYNC03'M'22E01 (labelled in red) covering the human Y-chromosomal derivative CHEK2 duplicon in Yq11.1/Yq11.21 on human (HSA), chimpanzee (PTR), gorilla (GGO), orangutan (PPY), rhesus macaque (MMU), pig-tailed macaque (MNE), baboon (PHA) and marmoset (CJA) metaphase chromosomes. The great ape chromosomal designations are given according to [65], for MMU, MNE and PHA according to [47] and for CJA according to [66]. White arrows indicate the ancestral CHEK2 locus.