The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae

Table 1 DNA sequence polymorphism summary statistics for TEP1

	n^b	length^c/bp	N ^d	S ^e	π_A^f	π_S^g	θ_A^h	θ_sⁱ	Taj D^j	Fu&Li D^j	Walls Q
TED domain
An. arabiensis (all^a)	35	661	47	32	3.87	8.92			2.07*	0.89	0.68***
TEP1s	11	828	5	7	0.31	0.91	2.67	1.27	-1.16	-0.71	0.00
TEP1r	24	839	6	6	0.20	0.44	0.25	0.85	-1.45	-1.71	0.42
Mbita (all^a)	46	736	44	38	3.81	10.58			2.93**	1.90**	0.76***
TEP1s	34	736	2	8	0.15	1.70	0.09	1.19	1.5	1.40**	0.2
TEP1r	12	840	2	1	0.15	0.09	0.10	0.17	-1.14	-1.33	0.00
Cameroon (all)	24	840	11	9	0.78	1.85	0.45	1.26	1.47	1.37	0.90***
TEP1s	9	840	2	6	0.17	1.58	0.11	1.15	1.57	1.37	1.00***
TEP1s/r	15	840	0	0	0.00	0.00	0.00	0.00	..	..	..
Burkina Faso (all r)	12	840	0	2	0.00	0.34	0.00	0.35	-0.05	-0.37	0.00
Region of *TEP1s* /r divergence
An. arabiensis
TEP1s	7	2292	8	14	0.22	1.15	0.21	1.19	0.18	0.05	0.16
TEP1r	20	2316	8	15	0.06	0.48			-1.61	-2.23	0.25
Mbita
TEP1s	19	2299	10	25	0.17	1.81	0.18	1.48	0.80	1.19	0.14
TEP1r	10	2320	4	7	0.07	0.32	0.09	0.51	-1.57	-1.63	0.18

a – samples were not at random with respect to allelic class, and thus do not exactly reflect natural allele frequencies
b – number of haplotypes sequenced
c – analyzed length of sequence
d – non-synonymous segregating sites
e – synonymous segregating sites
f – average pairwise genetic diversity at non-synonymous sites
g – average pairwise genetic diversity at synonymous sites
h – Watterson's estimate of 4 Nμ per site for non-synonymous sites
i – Watterson's estimate of 4 Nμ per site for synonymous sites
j – Tajimas D statistic and Fu & Li's D statistic calculated for synonymous sites only
k – Walls Q statistic

ISSN: 2730-7182