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Table 1 Different measures used for asserting domain combination tendencies

From: Just how versatile are domains?

Measure Abbr. Description Reference
Co-occurrence NCO Number of domains that are found at least once in the same proteins as the given domain [7]
Number of neighbours NN Number of direct neighbours found for a given domain [26]
Number of triplets NTRP For a given domain A, number of different combinations X – A – Y, where X and Y are domains or N- or C-termini [12]
Weighted bigram frequency index π i See original paper for exact definition [32]
Domain versatility index DV I Strength of the relationship between the number of occurrences and the number of neighbours this study