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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Molecular evolution of bovine Toll-like receptor 2 suggests substitutions of functional relevance

Figure 1

Average dN/dS ratio of a 20 AA sliding window along the protein sequence. The analysis is based on the complete dataset of 22 mammalian sequences. The predicted domain structure, position of polymorphic and positively selected (P > 0.95) sites is indicated. Sites displayed as "functional" refer to positions which were found to be crucial for ligand binding or heterodimerisation in human (additional file 7: Functional relevant TLR2 sites identified in former studies in human or mouse).

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