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Table 2 Multi-locus HKA test results for AVPR1B exons.

From: A complex selection signature at the human AVPR1B gene

Region

Fixed sub.

MLHKA

Multi-locus HKA

  

YRI

AA

EU

AS

EU

AS

  

ka

p b

ka

p b

ka

p b

ka

p b

Lc

p d

Lc

p d

Ex1

35

2.08

.086

2.06

.20

1.60

.54

0.66

.13

n.a.e

n.a.e

n.a.e

n.a.e

Ex2

25

3.77

.0046

3.38

.0093

3.56

.011

3.50

.011

35

.001

44

<.001

  1. a k (selection parameter) values from MLHKA test; k<1 means a reduction in polymorphism while k>1 means an excess of nucleotide variation;
  2. b p values for the MLHKA test;
  3. c likelihood (sum of deviations) for multi-locus HKA test;
  4. d p values from demographic coalescent simulations for multi-locus HKA;
  5. e not analyzed.