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Figure 1 | BMC Evolutionary Biology

Figure 1

From: Domain duplication, divergence, and loss events in vertebrate Msx paralogs reveal phylogenomically informed disease markers

Figure 1

MEME Domain Identification in the Msx Family. A) Conserved domains identified by MEME in a comparison of human MSX1 (Msx1_Hos) and the Msx proteins of cephalochordate, hemichordate, sea urchin, polychaete, and coral. The domains are named consecutively from the N-terminal to the C-terminal ends of the protein as Msx Homology (MH) domains 1–5. B) Conserved domains identified by MEME in a comparison of vertebrate Msx paralogs plus single Msx proteins from cephalochordate, tunicate, sea urchin, polychaete, and coral. The MH2 and MH5 domains include more amino acids (see Fig. 2) due to the increased sequence similarity within the vertebrate clade. These slightly larger domains are indicated by a "+". Taxon/gene abbreviations are listed in the methods.

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