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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Domain duplication, divergence, and loss events in vertebrate Msx paralogs reveal phylogenomically informed disease markers

Figure 2

LOGO Position Specific Scoring Matrices (PSSMs) identified by MEME. The first column shows the LOGO PSSMs identified for Msx1 orthologs from the MEME result shown in Fig. 1A; the second column shows the LOGO PSSMs identified for vertebrate Msx1, 2, 3 and Msx sequences from basal taxa from the MEME result shown in Fig. 1B. Note that the LOGO motif labeled "MH1N(&C)" refers to all the N-terminal MH1 domains in Figure 1A plus the C-terminal domain in the coral, Acropora. The second column LOGO labeled "MHIN or C" was a consensus motif found among the predominantly vertebrate taxa. The slightly longer MH2 and MH5 domains in this second column are indicated with a "+". Also note that the LOGOs on the third row illustrate the contiguous N8 amino acids plus the MH4 homeodomain. This N8 is considered as a portion of the MH3 linker that spans the MH2 and MH4 domains, as described in the text.

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