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Figure 2 | BMC Evolutionary Biology

Figure 2

From: Evolutionary conservation and changes in insect TRP channels

Figure 2

Phylogenetic tree of D. melanogaster , C. elegans , and mouse TRPV and TRPM channels. The phylogenetic tree was constructed from the amino acid sequences of channel-forming six transmembrane domains of D. melanogaster TRPV (DmNan and DmIav), TRPM (DmTRPM), C. elegans TRPV (Ocr-1, 2, 3, 4, and Osm-9), TRPM (Gtl-1, 2, and Gon-2), and mouse TRPV (mTRPV1, 2, 3, 4, 5, and 6), TRPM (mTRPM1, 2, 3, 4, 5, 6, 7, and 8) as in Fig. 1. TRPV and TRPM subfamily members are shown by red and green, respectively. Nematode and mouse TRPV and TRPM channels form independent clades, demonstrating that nematode and mouse have independently expanded these TRP channels.

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