Figure 6

Maestro score distributions for human mitochondrial and non-mitochondrial proteins. Maestro scoring system incorporates eight genomic-scale data sets (targeting sequence prediction, protein domain enrichment, presence of cis-regulatory motifs, yeast homology, ancestry, tandem-mass spectrometry, coexpression and transcriptional induction during mitochondrial biogenesis) for predicting nuclear encoded mitochondrial proteins [40]. The cutoff score of 5.65 is indicated as the vertical bar.