A multiple alignment of amino acid sequences of Bmp2/4/16 and other members of the TGFβ superfamily. The alignment is shown for the mature TGFβ ligand domain (SMART domain ID, SM00204). Amino acid residues conserved only among teleost bmp16 are shown in green, while those conserved in all Bmp2/4/16 sequences are shown in red. Amino acid residues conserved only in Bmp2/4 are shown in blue. Amino acid residues in the human Bmp2 that are recognized by receptors are shown with '#' .