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Table 1 Nucleotide and protein variation in the H2A variants analyzed.

From: The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues

  pAA (SE) pNT (SE) pS (SE) pN (SE) Z-testa Rb
H2A.Z-1 0.058 (0.009) 0.121 (0.008) 0.328 (0.016) 0.037 (0.006) 17.475** 1.3
H2A.Z-2 0.032 (0.006) 0.131 (0.011) 0.400 (0.020) 0.018 (0.003) 17.516** 1.4
H2A.Z-e 0.016 (0.007) 0.148 (0.013) 0.450 (0.031) 0.028 (0.009) 13.946** 1.2
Insects 0.024 (0.010) 0.203 (0.012) 0.611 (0.022) 0.037 (0.008) 24.826** 1.1
Fungi/Protists 0.309 (0.031) 0.385 (0.015) 0.710 (0.023) 0.260 (0.025) 12.886** 0.8
Overall 0.083 (0.011) 0.236 (0.019) 0.648 (0.024) 0.077 (0.009) 30.354** 0.9
  1. Average numbers of amino acid (pAA), nucleotide (pNT), synonymous (pS), and nonsynonymous (pN) nucleotide differences per site and Z-test of selection.
  2. Note.- SE, standard error; ** P < 0.001
  3. a H0: pN = pS; H1: pN <pS
  4. b Average transition/transversion ratio