Evolution of the class C GPCR Venus flytrap modules involved positive selected functional divergence

Table 1 Coefficients of functional divergence (θ) for all pairwise comparisons of the VFTMs.

	PBP	mGluR	CaSR	T1R	GB1	GB2
PBP	0	0.730 ± 0.076	0.761 ± 0.124	0.698 ± 0.091	0.833 ± 0.139	0.637 ± 0.100
mGluR	1.311	0.446	0.338 ± 0.106	0.446 ± 0.055	0.787 ± 0.109	0.737 ± 0.101
CaSR	1.43	0.413	0.459	0.001 ± 0.022	0.650 ± 0.141	0.906 ± 0.132
T1R	1.196	0.591	0.001	0.648	0.826 ± 0.147	0.915 ± 0.127
GB1	1.789	1.549	1.049	1.751	0.802	0.384 ± 0.123
GB2	1.013	1.334	2.36	2.467	0.485	1.061

The upper-right triangle shows the functional divergence (θ) values for all pairwise comparisons, data is presented as value ± standard error, the lower-left triangle shows the functional distance between two groups, the diagonal shows the functional branch length (b_F) values of each group, arbitrarily constraining b_F(PBP) = 0.

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