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Table 7 Average transcript density of lineage-specific breakpoints observed for regions of 125 kb around the arithmetic centre of the evolutionary breakpoint interval.

From: Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution

Feature investigated

Species

 

Chicken

Opossum

Cow/Dog

Mouse/Rat

Human

No. of evolutionary breakpoint intervals

83

25

166

120

56

Average size of the breakpoint interval (Mb)

0.16

0.24

0.27

0.35

0.39

Transcripts/Mb

29.76

27.76

17.52

16.20

20.32

Increase above the genome average transcript density

3.72-fold

3.72-fold

2.19-fold

2.03-fold

2.54-fold

  1. NB. Estimates of both the average size of the breakpoint interval and the transcript density are sensitive to the relative-fold sequence coverage of the respective genomes. However, calculating values for the increase above the genome average transcript density allows valid inter-genome comparisons to be made.