Table 2 Key structural domains predicted in the Pfam database.

RIG-I

Human

O95786

1–87

104–191

(0.69)

244–420

(7.1e-14)

655–734

(9.2e-15)

Xenopus

ENSXETP00000020202

103–189

(0.43)

303–434

(1.6e-10)

723–785

(1.3e-13)

Zebrafish

ENSDARP00000058175

(partial)

103–186

(3.7)

246–268

(0.019)

MDA5

Human

Q9BYX4

7–97

115–200

(2.4e-18)

305–493

(3.2e-22)

743–826

(1.1e-20)

Chicken

XP_422031

37–90

(15)

112–198

(7.8e-06)

298–485

(4.8e-20)

717–800

(5.6e-21)

936–944

(0.51)

Xenopus

ENSXETP00000028841

12–97

(0.073)

142–198

(0.002)

299–487

(7.7e-20)

719–802

(1.1e-21)

938–946

(8.6)

Fugu

ENSTRUP00000003254

10–96

(0.072)

110–196

(3.2e-05)

300–488

(6.4e-15)

711–794

(1.6e-19)

930–939

(1.1)

LGP2

Human

NP_077024

4–178

(1.3e-13)

392–475

(3.3e-21)

Chicken

ENSGALP00000005315

1–116

(4.3e-05)

521–532

(3.7)

Xenopus

ENSXETP00000004920

1–173

(1.5e-17)

395–478

(7.8e-24)

Fugu

ENSTRUP00000040150

3–172

(8.5e-19)

396–477

(9.3e-20)

DICER

Human

NP_803187

45–207

(1.9e-08)

499–556

(7.7e-17)

Chicken

NP_001035555

45–207

(5.1e-10)

499–556

(7.7e-17)

Xenopus

ENSXETP00000050382

(partial)

35–209

(6.9e-06)

Fugu

ENSTRUP00000014961

46–217

(7.3e-06)

499–556

(7.7e-17)

eIF4A

Human

AAV38682

56–223

(2.5e-63)

291–367

(1.3e-35)

Chicken

NP_989880

57–224

(6.7e-62)

292–368

(6.5e-36)

Xenopus

NP_001085314

56–223

(1.1e-62)

291–367

(6.5e-36)

Fugu

ENSTRUP00000005018

56–223

(5.7e-59)

291–367

(3.6e-36)