Skip to main content

Advertisement

Table 2 Key structural domains predicted in the Pfam database.

From: Origin and evolution of the RIG-I like RNA helicase gene family

  GenBank
Accession number
CARD1 CARD2 Res III DExD/H HELICc TFIIS-C
RIG-I        
Human O95786 1–87 104–191
(0.69)
  244–420
(7.1e-14)
655–734
(9.2e-15)
 
Xenopus ENSXETP00000020202   103–189
(0.43)
  303–434
(1.6e-10)
723–785
(1.3e-13)
 
Zebrafish ENSDARP00000058175
(partial)
  103–186
(3.7)
  246–268
(0.019)
  
MDA5        
Human Q9BYX4 7–97 115–200
(2.4e-18)
305–493
(3.2e-22)
  743–826
(1.1e-20)
 
Chicken XP_422031 37–90
(15)
112–198
(7.8e-06)
298–485
(4.8e-20)
  717–800
(5.6e-21)
936–944
(0.51)
Xenopus ENSXETP00000028841 12–97
(0.073)
142–198
(0.002)
299–487
(7.7e-20)
  719–802
(1.1e-21)
938–946
(8.6)
Fugu ENSTRUP00000003254 10–96
(0.072)
110–196
(3.2e-05)
300–488
(6.4e-15)
  711–794
(1.6e-19)
930–939
(1.1)
LGP2        
Human NP_077024     4–178
(1.3e-13)
392–475
(3.3e-21)
 
Chicken ENSGALP00000005315    1–116
(4.3e-05)
   521–532
(3.7)
Xenopus ENSXETP00000004920    1–173
(1.5e-17)
  395–478
(7.8e-24)
 
Fugu ENSTRUP00000040150    3–172
(8.5e-19)
  396–477
(9.3e-20)
 
DICER        
Human NP_803187     45–207
(1.9e-08)
499–556
(7.7e-17)
 
Chicken NP_001035555     45–207
(5.1e-10)
499–556
(7.7e-17)
 
Xenopus ENSXETP00000050382
(partial)
    35–209
(6.9e-06)
  
Fugu ENSTRUP00000014961     46–217
(7.3e-06)
499–556
(7.7e-17)
 
eIF4A        
Human AAV38682     56–223
(2.5e-63)
291–367
(1.3e-35)
 
Chicken NP_989880     57–224
(6.7e-62)
292–368
(6.5e-36)
 
Xenopus NP_001085314     56–223
(1.1e-62)
291–367
(6.5e-36)
 
Fugu ENSTRUP00000005018     56–223
(5.7e-59)
291–367
(3.6e-36)
 
  1. Note: The amino acid position of each domain is listed and the E values against the Pfam database are indicated in parentheses.