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Fig. 2 | BMC Evolutionary Biology

Fig. 2

From: Insights into the evolution of enzyme substrate promiscuity after the discovery of (βα)8 isomerase evolutionary intermediates from a diverse metagenome

Fig. 2

Performance of HMM profiles against UniProt and CAMERA databases. HisA, PriA, subHisA and ‘Transition Zone’ sequences are shown as red, blue, orange and green dots, respectively. UniProt codes corresponding to sequences removed to construct the HMM refined profile are indicated. The functionally characterized evolutionary intermediates from CAMERA database are marked as CAM1 and CAM2

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