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Table 1 Splice donors and acceptors of the Cxqdsx gene. Coding (exon) sequences are in uppercase text, while the splice donor/acceptor and succeeding/preceeding 12 nucleotides, respectively, are in lowercase. “Exon 4ex” denotes the alternate downstream splice donor of exon 4. Asterisk indicates the splice acceptor site deviates significantly from the genomic mean of 8.58 +/− 1.39 SE (see Methods)

From: Characterization of the doublesex gene within the Culex pipiens complex suggests regulatory plasticity at the base of the mosquito sex determination cascade

 

exon end

splice donor

intron

splice acceptor

next exon begin

No. purines

exon 1

AAAAAG

gtgggcttctttatct

intron 1

ctttttcccgtttcag

ATCCTTGCTT

11

exon 2

AAGGAG

gtaagttcgcaacctc

intron 2

cctcctctctttgcag

CCAATCATGC

12

exon 3a

TACCAG

gtacgtgtcttccgct

intron 3a

cattatatcatttcag

TCCCTCCAAA

8

exon 3b

GATCAG

gtgagtgctagaagtc

intron 3b

tattatcccctttcag

ACGATGAACT

10

exon 4

ACGAAG

gtatggccgagtgttc

intron 4

ttccgttcctacgcag

GTCAAGCCGT

10

exon 4ex

TAAAAT

gtacgcaagagattcg

intron 4ex

ttccgttcctacgcag

GTCAAGCCGT

10

exon 5

TGACAG

gtacttgaactaatta

intron 5

ccaaccaacaaaacag

CTCAGGCTGT

5*

exon 6

GCGAAG

gtgagttgagcattgt

intron 6

cttatcatcattacag

ATGCCGCTAG

9

consensus

 

gtrnk-----------

 

------------ncag