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Table 4 Functional distribution of HT genes

From: Horizontal gene transfer and genome evolution in Methanosarcina

COG category

Presence in Methanosarcina

Presence in Methanosarcinaceae

  

No.

Enz.

Tr.

1

2

3

No

Enz

Tr

2

3

4

5

6

Information storage and processing:

18 (9,7 %)

7 (11,7 %)

J

Translation, ribosomal structure and biogenesis

6

3

0

2

2

2

2

1

0

0

0

1

1

0

K

Transcription

7

1

0

5

1

1

3

0

0

0

0

0

2

1

L

Replication, recombination and repair

5

2

0

2

1

2

2

1

0

0

0

0

1

1

Cellular processes and signaling:

26 (14 %)

9 (15 %)

V

Defense mechanisms

11

7

3

4

5

2

1

1

0

0

1

0

0

0

T

Signal transduction mechanisms

5

2

0

3

2

0

1

0

0

0

0

0

0

1

M

Cell wall/membrane/envelope biogenesis

8

1

0

4

1

3

5

2

2

0

1

2

2

0

N

Cell motility

1

1

0

0

1

0

0

0

0

0

0

0

0

0

O

Posttranslational modification, protein turnover, chaperones

1

0

0

0

1

0

2

0

0

0

0

1

1

0

Metabolism:

95 (51,3 %)

37 (54 %)

C

Energy production and conversion

21

10

0

3

14

4

10

2

0

0

1

6

3

0

E

Amino acid transport and metabolism

25

10

8

1

13

11

9

5

1

0

0

2

1

6

F

Nucleotide transport and metabolism

7

5

0

1

4

2

3

2

0

0

0

0

0

3

G

Carbohydrate transport and metabolism

10

2

2

1

4

5

3

1

0

0

1

1

0

1

H

Coenzyme transport and metabolism

10

3

0

1

7

2

4

1

0

1

0

1

0

2

I

Lipid transport and metabolism

3

0

0

0

1

2

0

0

0

0

0

0

0

0

P

Inorganic ion transport and metabolism

16

2

9

2

9

5

6

0

5

0

0

0

1

5

Q

Secondary metabolites biosynthesis, transport and catabolism

3

0

0

0

2

1

2

1

0

0

0

1

0

1

Poorly characterized:

46 (24,8 %)

16 (23,5 %)

R

General function prediction only

31

10

2

10

13

8

11

2

0

0

0

3

2

6

S

Function unknown

15

0

0

1

4

10

5

0

0

0

0

1

3

1

  1. Tr. is the number of GOPs containing transporters, Enz. is the number of GOPs containing enzymes, numbers in the heading represent the number of genomes in GOP. All HT singletons were also included into this analysis