Fig. 2From: Evolutionary analysis of selective constraints identifies ameloblastin (AMBN) as a potential candidate for amelogenesis imperfectaLocation of putative translation initiation sites (TIS) in 30 mammalian and one crocodilian AMBN sequences. The arrows (−3, +4) point to nucleotide positions that play an essential role in the initiation of the translation. Two putatively functional TIS (squared ATGs on grey background in exons 1 and 2) are present in placental sequences, but a few exceptions, while only one TIS is identified in marsupials, platypus and crocodile. An additional, putatively functional TIS is present in cow AMBN Back to article page