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Fig. 8 | BMC Evolutionary Biology

Fig. 8

From: Hand/foot splitting and the ‘re-evolution’ of mesopodial skeletal elements during the evolution and radiation of chameleons

Fig. 8

C. calyptratus Gremlin 1 (Grem1) expression during autopodial morphogenesis. Grem1 is expressed in the mesenchyme of the autopodium anterior to the ZPA where a feedback loop is known to be present between Grem1 and SHH, Bmps, and FGF8 (a-f). Grem1 appears to decrease its anterior expression during digital plate formation in the forelimb (e) and hindlimb (f). During distal flattening and cleft formation, Grem1 does not appear ectopically between syndactylous digits (g-l)

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BMC Ecology and Evolution

ISSN: 2730-7182

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