From: The effects of natural selection across molecular pathways in Drosophila melanogaster
Gene | n c | D N | D S | P N | P S | P FET | Phenotype(s) |
---|---|---|---|---|---|---|---|
nonC | 1852 | 31 | 39 | 8 | 53 | 0.000076 | Hippo decrease |
 |  |  |  |  |  |  | Hedgehog increase |
Set2 | 1408 | 27 | 37 | 17 | 73 | 0.001521 | Hedgehog increase |
Nup153 | 1294 | 49 | 49 | 8 | 30 | 0.001623 | Hedgehog decrease |
 |  |  |  |  |  |  | RTK-Ras-ERK signaling decrease |
 |  |  |  |  |  |  | RTK-Ras-ERK signaling increase |
Kib | 1076 | 5 | 26 | 0 | 62 | 0.003269 | Decreased cell viability |
pcm | 1072 | 29 | 28 | 4 | 19 | 0.005061 | Blood TE activity |
Cnot4 | 860 | 20 | 20 | 9 | 34 | 0.005227 | Hippo decrease |
ZC3H3 | 414 | 9 | 8 | 6 | 31 | 0.007610 | Hippo increase |
 |  |  |  |  |  |  | RTK-Ras-ERK signaling decrease |
Nup205 | 781 | 11 | 21 | 2 | 28 | 0.007613 | Wnt increase |
Dref | 554 | 6 | 20 | 0 | 29 | 0.007942 | Hedgehog increase |
 |  |  |  |  |  |  | RTK-Ras-ERK signaling decrease |
Sik3 | 571 | 6 | 7 | 4 | 37 | 0.008072 | Hippo decrease |
RasGAP1 | 979 | 6 | 26 | 1 | 54 | 0.009106 | Innate immunity |
 |  |  |  |  |  |  | RTK-Ras-ERK signaling increase |