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Table 3 Panther pathways gene enrichment analysis of genes containing variants with an Fst score > = 0.75

From: Identification of genomic variants putatively targeted by selection during dog domestication

PANTHER Pathways

Canis familiaris - REFLIST [19662]

Genes with putatively functional variants [848]

Expected number

Fold enrichment

P-value

Unclassified

17318

712

746.91

-

0.00E00

Adrenaline and noradrenaline biosynthesis

26

9

1.12

+

4.19E-08

Axon guidance mediated by netrin

38

7

1.64

+

2.31E-01

Dopamine receptor mediated signaling pathway

51

8

2.20

+

2.97E-01

Nicotine pharmacodynamics pathway

31

6

1.34

+

3.87E-01

Alpha adrenergic receptor signaling pathway

22

5

.95

+

4.45E-01

Gonadotropin releasing hormone receptor pathway

225

19

9.70

+

7.74E-01