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Table 3 Panther pathways gene enrichment analysis of genes containing variants with an Fst score > = 0.75

From: Identification of genomic variants putatively targeted by selection during dog domestication

PANTHER Pathways Canis familiaris - REFLIST [19662] Genes with putatively functional variants [848] Expected number Fold enrichment P-value
Unclassified 17318 712 746.91 - 0.00E00
Adrenaline and noradrenaline biosynthesis 26 9 1.12 + 4.19E-08
Axon guidance mediated by netrin 38 7 1.64 + 2.31E-01
Dopamine receptor mediated signaling pathway 51 8 2.20 + 2.97E-01
Nicotine pharmacodynamics pathway 31 6 1.34 + 3.87E-01
Alpha adrenergic receptor signaling pathway 22 5 .95 + 4.45E-01
Gonadotropin releasing hormone receptor pathway 225 19 9.70 + 7.74E-01