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Table 4 Putatively functional variants with an Fst score > = 0.75 in genes in the ‘adrenaline and noradrenaline biosynthesis’ pathway

From: Identification of genomic variants putatively targeted by selection during dog domestication

Gene ID

Gene name

Position [chr:position]

Nucleotide change [Dog/Wolf]

Predicted effect

DDC

Dopa decarboxylase [Aromatic-L-Amino-Acid decarboxylase]

18:1806717

C/T

Missense [R/Q]

MAOA

Amine oxidase [flavin-containing] A

X:37747023

T/C

3‘-UTR

MAOB

Amine oxidase [flavin-containing] B

X:37766049

C/T

3‘-UTR

SLC6A3

Sodium-dependent dopamine transporter member 3

34:11239621

C/T

Splice region, intronic

SLC6A17

Sodium-dependent neutral amino acid transporter member 17

6:41776709

C/A

3‘-UTR

SLC6A19

Sodium-dependent neutral amino acid transporter member 19

34:11329939

G/A

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30614788

C/T

Missense [S/N]

SNAP29

Synaptosomal-associated protein 29

26:30607948

G/A

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30607975

T/C

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608088

T/C

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608209

G/A

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608212

T/C

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608354

A/G

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608375

C/T

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608864

A/G

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:30608989

C/T

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:37750228

T/A

3‘-UTR

SNAP29

Synaptosomal-associated protein 29

26:38554416

G/A

3‘-UTR

STX7

Syntaxin-7

1:25559797

T/C

3‘-UTR

TH

Tyrosine 3-monooxygenase

18:46331581

G/A

Splice region, intronic