Fig. 2
From: Binding interface change and cryptic variation in the evolution of protein-protein interactions
A network visualisation of duplicate genes and their known interactions. Duplicate genes with known interfaces from the PISA database are shown in blue. Duplicate genes with no known interfaces are shown in red. Singleton genes that interact with duplicates are shown in grey. Physical interactions between the protein products of these genes were extracted from the PISA [22] and BioGrid [30] databases and form the edges in the network. The size of the blue nodes is scaled with the number of known interfaces identified in the PISA database with larger nodes containing a larger number of known interfaces