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Fig. 3 | BMC Evolutionary Biology

Fig. 3

From: Binding interface change and cryptic variation in the evolution of protein-protein interactions

Fig. 3

Density and frequency distributions of the total number of interactions observed per duplicate pair. In the density distribution the blue curve represents the density of interactions from all interactions contained in BioGrid. The red curve shows the density of interactions from the multiple confidence network (interactions must be observed in two separate studies). The density distribution describes the probability of a duplicate pair having a specific number of interactions and the area of each curve sums to 1. The insets show the frequency distributions of interactions per duplicate pair with interactions from all interactions contained in BioGrid (top) and interactions from the multiple confidence interaction network (bottom)

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