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Fig. 4 | BMC Evolutionary Biology

Fig. 4

From: Binding interface change and cryptic variation in the evolution of protein-protein interactions

Fig. 4

The difference in selection on interface and non-interface residues in duplicates with conserved and diverged interactions. The Boxplots show the proportion of residues in interfaces and non-interface regions under negative selection or neutrally evolving for duplicate pairs. Duplicate pairs showing conserved interactions at the interface have been separated from those that show diverged interactions. Categories of interface and non-interface residues are shown on the x axis. Boxplots for negatively selected residues are shown in grey and neutrally evolving residues plots are shown in white

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