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Table 1 Relationship between change in interfaces and change in specificity, using the multiple confidence network. Values based on all interactions in BioGrid are shown in parentheses

From: Binding interface change and cryptic variation in the evolution of protein-protein interactions

   Interface
   Conserved Diverged
Interaction Conserved 18 (18) 34 (56)
  Diverged 12 (12) 106 (84)