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Fig. 7 | BMC Evolutionary Biology

Fig. 7

From: A pancreatic exocrine-like cell regulatory circuit operating in the upper stomach of the sea urchin Strongylocentrotus purpuratus larva

Fig. 7

Proposed model of sea urchin pancreatic exocrine-like specification and differentiation. a The schemes show the development of exocrine-like cells from late gastrula (left) to larva (right). The right drawing also shows the localization of putative endocrine cells that are positive for antibody staining of a member of the insulin family (ILP-1+ cells). Note that we do not know if the ILP-1+ cells in the upper stomach are simply adjacent to the pancreatic exocrine-like cells or there are stomach cells which share both features. b Summary of regulatory interactions occurring in pancreatic exocrine-like cells unraveled by this study. Different genes are shown with different colors. The wiring among the genes is shown with solid lines. Arrows represent positive regulation, bars represent repression, and dashed lines indicate signaling events. Question marks in the food input means that the mechanism and the genes involved in the pathway are not known. Abbreviations: fg, foregut; hg, hindgut; in, intestine; mo, mouth

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